ITGB1 Antikörper
Kurzübersicht für ITGB1 Antikörper (ABIN960569)
Target
Alle ITGB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This monoclonal antibody (subclass IgG1) binds to human b1-integrin chain present on tumor cells. BV7 is active on HT-29 colon carcinoma cells and on HCCP-2998 tumor cells. BV7 binds to several other tumor cells (MG3 osteosarcoma, A375 melanoma, MHCC-1410 and Lovo colon carcinoma) but does not affect adhesion to endothelial cells.
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Aufreinigung
- Purified
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Immunogen
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Type of Immunogen: Native protein -
Isotyp
- IgG1
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Applikationshinweise
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Approved: Flo, Func, IP, WB
Usage: For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For neutralization of biological activity in vitro dilutions have to be made according to the amounts of beta1 integrin to be inactivated. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, 0.1 % BSA
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 4°C. Store undiluted.
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- ITGB1 (Integrin beta 1 (ITGB1))
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Andere Bezeichnung
- ITGB1 / Integrin Beta 1 / CD29
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Hintergrund
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Name/Gene ID: ITGB1
Family: Integrin
Synonyms: ITGB1, CD29, CD29 antigen, Integrin beta-1, MDF2, MSK12, Integrin VLA-4 beta subunit, VLA-BETA, VLAB, Beta 1 integrin, FNRB, GPIIA, Integrin Beta 1, VLA-4 subunit beta -
Gen-ID
- 3688
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UniProt
- P05556
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Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom
Target
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